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LSP-249

LSP-249
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.
Catalog No. T11885Cas No. 1801253-04-2
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Purity:99.27%
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LSP-249

Catalog No. T11885Cas No. 1801253-04-2

LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$40In Stock
5 mg$64In Stock
10 mg$97In Stock
25 mg$197In Stock
50 mg$328In Stock
100 mg$538In Stock
1 mL x 10 mM (in DMSO)$70In Stock
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Product Introduction

Bioactivity
Description
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.
Targets&IC50
Kallikrein:< 100 nM (EC50)
Chemical Properties
Molecular Weight431.92
FormulaC24H22ClN5O
Cas No.1801253-04-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 31.25 mg/mL (69.45 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3152 mL11.5762 mL23.1524 mL115.7622 mL
5 mM0.4630 mL2.3152 mL4.6305 mL23.1524 mL
10 mM0.2315 mL1.1576 mL2.3152 mL11.5762 mL
20 mM0.1158 mL0.5788 mL1.1576 mL5.7881 mL
50 mM0.0463 mL0.2315 mL0.4630 mL2.3152 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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