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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $44 | 5 days |
Description | Mal-amido-PEG12-NHS ester is a polyethylene glycol (PEG)-derived linker used in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the conjugation of target-specific ligands for protein degradation[1]. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 865.92 |
Formula | C38H63N3O19 |
Cas No. | 2101722-60-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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