Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | MAO-B-IN-18 is a potent, selective inhibitor of MAO B with IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects against hydrogen peroxide-induced damage in neuroblastoma and astrocyte cultures [1]. |
Targets&IC50 | MAO-B (human):52 nM, MAO-A (human):14 μM |
In vitro | MAO-B-IN-18 (Compound 20; 0.1, 0.5, 1, 5 μM) protects neuroblastoma cells in SH-SY5Y cultures from pro-oxidative damage through a pathway involving moderate ROS scavenging [1]. When co-incubated with hydrogen peroxide (400 μM), MAO-B-IN-18 (5 μM) sustains the viability of DI TNC1 astrocyte cell lines at levels comparable to those of the positive control quercetin at a high dose (75 μM) [1]. |
Molecular Weight | 458.47 |
Formula | C25H22N4O5 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.