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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM). |
Targets&IC50 | β2-adrenoceptor:68 nM |
In vitro | Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment downregulates NF-κB and increases β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages [1]. |
In vivo | Metaproterenol (Zucker diabetic fatty rats; 12 weeks ) treatment, decreases monocyte activation as well as pro-inflammatory and pro-fibrotic responses in the kidneys and heart. Metaproterenol might have protective effects against diabetic renal and cardiovascular complications[1]. |
Alias | Orciprenaline |
Molecular Weight | 211.26 |
Formula | C11H17NO3 |
Cas No. | 586-06-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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