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Methyl L-pyroglutamate

Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) shows anti-inflammatory activity. Methyl L-pyroglutamate is isolated from Portulaca oleracea L..

Catalog No. T12016Cas No. 4931-66-2

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Purity:99.81%

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COA HNMR GC

Methyl L-pyroglutamate

Catalog No. T12016Cas No. 4931-66-2

Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) shows anti-inflammatory activity. Methyl L-pyroglutamate is isolated from Portulaca oleracea L..

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Pack Size	Price	Availability	Quantity
500 mg	$42	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Product Introduction

Bioactivity

Description	Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) shows anti-inflammatory activity. Methyl L-pyroglutamate is isolated from Portulaca oleracea L..
Alias	L-Pyroglutamic acid methyl ester, (S)-Methyl 5-oxopyrrolidine-2-carboxylate

Chemical Properties

Molecular Weight	143.14
Formula	C₆H₉NO₃
Cas No.	4931-66-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/ml (384.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.9862 mL	34.9308 mL	69.8617 mL	349.3084 mL
5 mM	1.3972 mL	6.9862 mL	13.9723 mL	69.8617 mL
10 mM	0.6986 mL	3.4931 mL	6.9862 mL	34.9308 mL
20 mM	0.3493 mL	1.7465 mL	3.4931 mL	17.4654 mL
50 mM	0.1397 mL	0.6986 mL	1.3972 mL	6.9862 mL
100 mM	0.0699 mL	0.3493 mL	0.6986 mL	3.4931 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Keywords

inhibitInhibitorMethyl 5-oxopyrrolidine-2-carboxylateMethyl L pyroglutamateMethyl LpyroglutamateMethyl L-pyroglutamate