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Momordicoside A
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Catalog No. TN1941Cas No. 75801-95-5
Momordicoside A is a triterpenoid saponin compound isolated from bitter melon (Momordica charantia L.), which possesses a variety of biological activities, including inhibition of protein tyrosine phosphatase (PTP1B), and can be used in the treatment of type 2 diabetes. In addition, Momordicoside A has anti-inflammatory, antioxidant, antitumor, and anti-HIV/AIDS potentials.
Momordicoside A
😃Good
Catalog No. TN1941Cas No. 75801-95-5
Momordicoside A is a triterpenoid saponin compound isolated from bitter melon (Momordica charantia L.), which possesses a variety of biological activities, including inhibition of protein tyrosine phosphatase (PTP1B), and can be used in the treatment of type 2 diabetes. In addition, Momordicoside A has anti-inflammatory, antioxidant, antitumor, and anti-HIV/AIDS potentials.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $564 | Backorder | |
| 10 mg | $946 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,150 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Momordicoside A is a triterpenoid saponin compound isolated from bitter melon (Momordica charantia L.), which possesses a variety of biological activities, including inhibition of protein tyrosine phosphatase (PTP1B), and can be used in the treatment of type 2 diabetes. In addition, Momordicoside A has anti-inflammatory, antioxidant, antitumor, and anti-HIV/AIDS potentials. |
| In vitro | Methods: A rapid, simple, and accurate method for the determination of Momordicoside A was established using solid phase extraction (SPE) followed by high performance liquid chromatography (HPLC). Results: Samples were processed by SPE on carboplatin cartridges (3 mL/250 mg) and then determined by HPLC on a C18 column (4.6 mm id x 250 mm, 5 μm) with a mobile phase of V(acetonitrile):V(50 mmol/L potassium dihydrogen phosphate buffer) = 25:20:60 (0.8 mL/min) and UV detection. The calibration curve was linear in the range of 10 mg/L to 1,000 mg/L (r2 = 0.9992). [2] |
| Molecular Weight | 817.01 |
| Formula | C42H72O15 |
| Cas No. | 75801-95-5 |
| Smiles | C[C@H]([C@H](O)[C@@H](O)[C@@H](O)C(C)(C)O)[C@H]1CC[C@@]2(C)[C@@H]3CC=C4[C@@H](CC[C@H](O[C@@H]5O[C@H](CO[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@H]5O)C4(C)C)[C@]3(C)CC[C@]12C |
| Relative Density. | 1.36 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | store at 4°C | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80.00 mg/mL (97.92 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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