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N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

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Catalog No. T12156Cas No. 97627-24-2

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

🥰Excellent
Purity: 99.83%
Catalog No. T12156Cas No. 97627-24-2
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.
Pack SizePriceAvailabilityQuantity
1 mg$37In Stock
5 mg$85In Stock
10 mg$143In Stock
25 mg$289In Stock
50 mg$463In Stock
100 mg$745In Stock
500 mg$1,490In Stock
1 mL x 10 mM (in DMSO)$94In Stock
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Purity:99.83%
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Product Introduction

Bioactivity
Description
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.
In vivo
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg.?The activity seen with 30 mg/kg 37 is still present 4 h postdose.?Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol.?The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures[1].
Chemical Properties
Molecular Weight261.71
FormulaC13H12ClN3O
Cas No.97627-24-2
SmilesCc1cccc(Cl)c1NC(=O)Nc1ccncc1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (458.52 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8210 mL19.1051 mL38.2102 mL191.0512 mL
5 mM0.7642 mL3.8210 mL7.6420 mL38.2102 mL
10 mM0.3821 mL1.9105 mL3.8210 mL19.1051 mL
20 mM0.1911 mL0.9553 mL1.9105 mL9.5526 mL
50 mM0.0764 mL0.3821 mL0.7642 mL3.8210 mL
100 mM0.0382 mL0.1911 mL0.3821 mL1.9105 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

N(2Chloro6methylphenyl)N'4pyridinylureaN-(2-Chloro-6-methylphenyl)-N'-4-pyridinylureaN (2 Chloro 6 methylphenyl) N' 4 pyridinylureaInhibitorinhibit
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