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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $33 | In Stock | |
5 mg | $76 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $397 | In Stock | |
100 mg | $589 | In Stock | |
500 mg | $1,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $84 | In Stock |
Description | HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx. |
In vitro | HUP30 inhibits phenylephrine induced aortic contraction with an IC50 value of 3.9 μ M. HUP30 (100 μ M) increases cGMP levels in the aorta stimulated by adrenaline. HUP30 has an antispasmodic effect on the 25/30 mM K+constricted rat aortic ring, with an IC50 value of 7.5 μ M. HUP30 (3-100 μ M) inhibits phenylephrine induced extracellular Ca2+ influx and Ca2+ mobilization. HUP30 (10-100 μ M) inhibits current in single tailed artery muscle cells [1]. |
Molecular Weight | 305.35 |
Formula | C14H15N3O3S |
Cas No. | 312747-21-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 18.0 mg/mL (59.0 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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