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NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM) with permanent charge and low membrane permeability. It demonstrates minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100 μM) and maintains hERG channel maturation without triggering a heat shock response or degrading Hsp90α-dependent client proteins [1].
Pack Size | Price | Availability | Quantity |
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5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM) with permanent charge and low membrane permeability. It demonstrates minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100 μM) and maintains hERG channel maturation without triggering a heat shock response or degrading Hsp90α-dependent client proteins [1]. |
Molecular Weight | 604.68 |
Formula | C31H35F3N2O5S |
Storage | Shipping with blue ice. |
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