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Opipramol
🥰Excellent
Catalog No. T61376Cas No. 315-72-0
Alias G-33040, G33040, Ensidon
Opipramol (Ensidon) is a compound with antidepressant activity that attenuates cocaine-seeking behavior in a rat model of self-administration.Opipramol is a sigma (σ) receptor agonist with anxiolytic activity and may be used in the study of neurological disorders.
Opipramol
🥰Excellent
Purity: 99.98%
Catalog No. T61376Alias G-33040, G33040, EnsidonCas No. 315-72-0
Opipramol (Ensidon) is a compound with antidepressant activity that attenuates cocaine-seeking behavior in a rat model of self-administration.Opipramol is a sigma (σ) receptor agonist with anxiolytic activity and may be used in the study of neurological disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $96 | In Stock |
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Purity:99.98%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Opipramol (Ensidon) is a compound with antidepressant activity that attenuates cocaine-seeking behavior in a rat model of self-administration.Opipramol is a sigma (σ) receptor agonist with anxiolytic activity and may be used in the study of neurological disorders. |
| Targets&IC50 | [3H] dopamine:5.5 μ, sigma recognition site:50 nM (Ki) |
| In vitro | Opipramol potently binds to the sigma recognition site with a Ki value of 50 nM. Opipramol also inhibits the uptake of [3H] dopamine in crude synaptic preparations with an IC50 value of 5.5 μM. [1] |
| In vivo | Opipramol has been shown to significantly increase dopamine release in vivo by intraperitoneal injection (dose range 5-50 mg/kg). [2] |
| Alias | G-33040, G33040, Ensidon |
| Molecular Weight | 363.5 |
| Formula | C23H29N3O |
| Cas No. | 315-72-0 |
| Smiles | OCCN1CCN(CC1)CCCN2C=3C=CC=CC3C=CC=4C=CC=CC42 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (220.08 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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