Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 34.00 | |
25 mg | In stock | $ 55.00 | |
50 mg | In stock | $ 80.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki of 32.6 μM. |
Targets&IC50 | TPH(ki):ki:32.6 μM , TPH:32.6 μM (Ki) |
In vivo | 4-Ethynyl-L-phenylalanine (30 mg/kg; i.p.) decreases in 5-HT and 5-HIAA levels in the rat midbrain but not in tissue. It is not inhibiting the aromatic amino acid decarboxylase. It has a low affinity for various recombinant 5-HT receptors. |
Synonyms | 4-Ethynyl-L-phenylalanine |
Molecular Weight | 189.21 |
Formula | C11H11NO2 |
CAS No. | 278605-15-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1M HCl: 1M HCl : 216.0 mg/mL (1141.6 mM), ultrasonic and adjust pH to 1 with HCl
DMSO: 2.0 mg/mL (10.6 mM), sonification is recommended.
1M NaOH: : 216.0 mg/mL (1141.6 mM), ultrasonic and adjust pH to 11 with NaOH
You can also refer to dose conversion for different animals. More
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p-Ethynylphenylalanine 278605-15-5 Metabolism Others Hydroxylase 4-Ethynyl-L-phenylalanine inhibitor inhibit