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PARP14 inhibitor H10

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Catalog No. T12366Cas No. 2084811-68-5

PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM

PARP14 inhibitor H10

PARP14 inhibitor H10

😃Good
Catalog No. T12366Cas No. 2084811-68-5
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
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1 mg$92835 days
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Product Introduction

Bioactivity
Description
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
Targets&IC50
PARP14:490 nM, PARP1:
Chemical Properties
Molecular Weight557.58
FormulaC24H27N7O7S
Cas No.2084811-68-5
Relative Density.1.50 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 62.5 mg/mL (112.09 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7935 mL8.9673 mL17.9346 mL89.6732 mL
5 mM0.3587 mL1.7935 mL3.5869 mL17.9346 mL
10 mM0.1793 mL0.8967 mL1.7935 mL8.9673 mL
20 mM0.0897 mL0.4484 mL0.8967 mL4.4837 mL
50 mM0.0359 mL0.1793 mL0.3587 mL1.7935 mL
100 mM0.0179 mL0.0897 mL0.1793 mL0.8967 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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