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Pedaliin
😃Good
Catalog No. TN5546Cas No. 22860-72-6
Alias Pedalitin 6-O-glucoside, Pedalin, Glucosyl-6-pedalitin
Pedaliin is a flavonoid extracted from the above-ground parts of sesame (Sesamum indicum L) and the Tibetan medicine Dracocephalum tanguticum Maxim.Pedaliin has shown antioxidant and anticancer effects against colon cancer in vitro, and can be used in the study of cardiovascular diseases.
Pedaliin
😃Good
Purity: 99.96%
Catalog No. TN5546Alias Pedalitin 6-O-glucoside, Pedalin, Glucosyl-6-pedalitinCas No. 22860-72-6
Pedaliin is a flavonoid extracted from the above-ground parts of sesame (Sesamum indicum L) and the Tibetan medicine Dracocephalum tanguticum Maxim.Pedaliin has shown antioxidant and anticancer effects against colon cancer in vitro, and can be used in the study of cardiovascular diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $998 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,250 | Backorder |
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Purity:99.96%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pedaliin is a flavonoid extracted from the above-ground parts of sesame (Sesamum indicum L) and the Tibetan medicine Dracocephalum tanguticum Maxim.Pedaliin has shown antioxidant and anticancer effects against colon cancer in vitro, and can be used in the study of cardiovascular diseases. |
| Targets&IC50 | BSA glycation:41.8 μM |
| In vitro | Pedaliin dose-dependently attenuates the growth of human colon cancer cells, HT29 and HCT116, with concentrations ranging from 0 to 35 μM after 72 hours of treatment[2]. With a concentration range of 3.5-35 μM, a 30-minute incubation at 37 ℃, Pedaliin exhibits ferric reducing antioxidant power (FRAP)[1]. Under non-cytotoxic conditions, Pedaliin at 7 μM for 48 hours alleviates the invasion and migration of HT29 and HCT116 cells[1]. Additionally, Pedaliin, at a volume of 20 μL, demonstrates high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, oxygen radical absorbance capacity (ORAC), and in vitro antiglycation activities. It also inhibits BSA glycation with an IC50 value of 41.8 μM[1]. |
| Alias | Pedalitin 6-O-glucoside, Pedalin, Glucosyl-6-pedalitin |
| Molecular Weight | 478.4 |
| Formula | C22H22O12 |
| Cas No. | 22860-72-6 |
| Smiles | OC1=C2C(OC(=CC2=O)C3=CC(O)=C(O)C=C3)=CC(OC)=C1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O |
| Relative Density. | 1.674 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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