Pedaliin is a flavonoid extracted from the above-ground parts of sesame (Sesamum indicum L) and the Tibetan medicine Dracocephalum tanguticum Maxim.Pedaliin has shown antioxidant and anticancer effects against colon cancer in vitro, and can be used in the study of cardiovascular diseases.

Pedaliin dose-dependently attenuates the growth of human colon cancer cells, HT29 and HCT116, with concentrations ranging from 0 to 35 μM after 72 hours of treatment[2]. With a concentration range of 3.5-35 μM, a 30-minute incubation at 37 ℃, Pedaliin exhibits ferric reducing antioxidant power (FRAP)[1]. Under non-cytotoxic conditions, Pedaliin at 7 μM for 48 hours alleviates the invasion and migration of HT29 and HCT116 cells[1]. Additionally, Pedaliin, at a volume of 20 μL, demonstrates high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, oxygen radical absorbance capacity (ORAC), and in vitro antiglycation activities. It also inhibits BSA glycation with an IC50 value of 41.8 μM[1].