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Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $43 | In Stock | |
25 mg | $85 | In Stock | |
50 mg | $145 | In Stock | |
100 mg | $247 | In Stock |
Description | Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects. |
Targets&IC50 | 6-phosphogluconate dehydrogenase:38.5 μM |
In vivo | Physcion modulates the expression of defense-related genes and enhances the expression of leaf-specific thiol compounds in barley leaves, thereby controlling powdery mildew. |
Alias | Rheochrysidin, Physcione, Parietin |
Molecular Weight | 284.26 |
Formula | C16H12O5 |
Cas No. | 521-61-9 |
Smiles | O=C1C=2C(C(=O)C=3C1=CC(C)=CC3O)=C(O)C=C(OC)C2 |
Relative Density. | 1.448 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O: Insoluble DMSO: Insoluble |
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