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PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K inhibition following UV light irradiation and has been shown to enhance antitumor effects [1]. This compound has potential for use in precisely controlled cancer therapeutics.
Pack Size | Price | Availability | Quantity |
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5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K inhibition following UV light irradiation and has been shown to enhance antitumor effects [1]. This compound has potential for use in precisely controlled cancer therapeutics. |
In vitro | PI3K-IN-41 (compound 2) at a concentration of 10 nM reduces AKT phosphorylation in HGC-27 cells and inhibits colony formation in HGC-27 cells at concentrations ranging from 1-10 μM following ultraviolet irradiation for 5, 15, and 30 minutes [1]. |
Molecular Weight | 911.88 |
Formula | C45H39F2N5O12S |
Storage | Shipping with blue ice. |
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