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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively. This compound also induces apoptosis and is utilized in cancer research [1]. |
In vitro | PI3K/VEGFR2-IN-1 (compound 8; 1.56-100 µM; 24 h; HePG2, MCF-7, Hela, and PC3 cells) dose-dependently inhibits proliferation, while at a concentration of 10 mg/mL and 24-hour exposure, it induces G1/S phase cell cycle arrest and apoptosis in MCF-7 and Hela cells [1]. |
Molecular Weight | 343.83 |
Formula | C17H14ClN3OS |
Cas No. | 2851067-08-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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