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Promethazine hydrochloride

Catalog No. T0445LCas No. 58-33-3
Alias Promethazine HCl, Phenergan

Promethazine hydrochloride (Promethazine HCl) , the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.

Promethazine hydrochloride

Promethazine hydrochloride

Purity: 95.36%
Catalog No. T0445LAlias Promethazine HCl, PhenerganCas No. 58-33-3
Promethazine hydrochloride (Promethazine HCl) , the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
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1 g$29In Stock
5 g$40In Stock
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Purity:95.36%
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Product Introduction

Bioactivity
Description
Promethazine hydrochloride (Promethazine HCl) , the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
AliasPromethazine HCl, Phenergan
Chemical Properties
Molecular Weight320.88
FormulaC17H20N2S·HCl
Cas No.58-33-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (171.4 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1164 mL15.5821 mL31.1643 mL155.8215 mL
5 mM0.6233 mL3.1164 mL6.2329 mL31.1643 mL
10 mM0.3116 mL1.5582 mL3.1164 mL15.5821 mL
20 mM0.1558 mL0.7791 mL1.5582 mL7.7911 mL
50 mM0.0623 mL0.3116 mL0.6233 mL3.1164 mL
100 mM0.0312 mL0.1558 mL0.3116 mL1.5582 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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