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PROTAC CDK9 Degrader-1
🥰Excellent
Catalog No. T5438Cas No. 2118356-96-8
PROTAC CDK9 Degrader-1 is a selective PROTAC CDK9 degrader composed of a cereblon ligand and a CDK9 ligand.
PROTAC CDK9 Degrader-1
🥰Excellent
Catalog No. T5438Cas No. 2118356-96-8
PROTAC CDK9 Degrader-1 is a selective PROTAC CDK9 degrader composed of a cereblon ligand and a CDK9 ligand.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $129 | In Stock | |
| 5 mg | $331 | In Stock | |
| 10 mg | $529 | In Stock | |
| 25 mg | $858 | In Stock | |
| 50 mg | $1,180 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $446 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PROTAC CDK9 Degrader-1 is a selective PROTAC CDK9 degrader composed of a cereblon ligand and a CDK9 ligand. |
| In vitro | In HCT116 cells, PROTAC CDK9 Degrader-1 (Compound 3) (2.5-20 μM; 6 h) induced CDK9 degradation in a dose-dependent manner.[1] |
| Molecular Weight | 613.66 |
| Formula | C33H35N5O7 |
| Cas No. | 2118356-96-8 |
| Smiles | O=C(NC1=NNC(=C1)C2CCC2)CC3=CC=C(OCCCCCOC4=CC=CC=5C(=O)N(C(=O)C45)C6C(=O)NC(=O)CC6)C=C3 |
| Relative Density. | 1.390 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (130.37 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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