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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $153 | 35 days | |
1 mg | $280 | 35 days | |
5 mg | $660 | 35 days | |
10 mg | $1,170 | 35 days |
Description | PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes. |
Targets&IC50 | PTP1B:8 μM (IC50) |
In vitro | In CHO cells overexpressing human IR, PTP1B-IN-4 (250 µM) stimulates the phosphorylation of insulin receptors. PTP1B-IN-4 induces phosphorylation of IRS-1 and Akt which are proteins downstream of the insulin receptor[3]. |
Alias | NUN 17724, PTP1B-inhibitor-2, PTP1B IN 2, PTP1B-IN-2, PTP1B-inhibitor-4, FRJ, PTP1B inhibitor 4, NUN17724, PTP1B inhibitor 2, PTP1BIN2, NUN-17724 |
Molecular Weight | 741.45 |
Formula | C26H19Br2N3O7S3 |
Cas No. | 765317-72-4 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (121.4 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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