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PTP1B-IN-4
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Catalog No. T24073Cas No. 765317-72-4
Alias PTP1B-inhibitor-4, PTP1B-inhibitor-2, PTP1B-IN-2, PTP1BIN2, PTP1B inhibitor 4, PTP1B inhibitor 2, PTP1B IN 2, NUN-17724, NUN17724, NUN 17724, FRJ
PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
PTP1B-IN-4
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Catalog No. T24073Alias PTP1B-inhibitor-4, PTP1B-inhibitor-2, PTP1B-IN-2, PTP1BIN2, PTP1B inhibitor 4, PTP1B inhibitor 2, PTP1B IN 2, NUN-17724, NUN17724, NUN 17724, FRJCas No. 765317-72-4
PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 μg | $153 | 35 days | |
| 1 mg | $280 | 35 days | |
| 5 mg | $660 | 35 days | |
| 10 mg | $1,170 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes. |
| Targets&IC50 | PTP1B:8 μM (IC50) |
| In vitro | In CHO cells overexpressing human IR, PTP1B-IN-4 (250 µM) stimulates the phosphorylation of insulin receptors. PTP1B-IN-4 induces phosphorylation of IRS-1 and Akt which are proteins downstream of the insulin receptor[3]. |
| Alias | PTP1B-inhibitor-4, PTP1B-inhibitor-2, PTP1B-IN-2, PTP1BIN2, PTP1B inhibitor 4, PTP1B inhibitor 2, PTP1B IN 2, NUN-17724, NUN17724, NUN 17724, FRJ |
| Molecular Weight | 741.45 |
| Formula | C26H19Br2N3O7S3 |
| Cas No. | 765317-72-4 |
| Relative Density. | 1.812 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (121.4 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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