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Raxibacumab
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Catalog No. T78310Cas No. 565451-13-0
Alias ABthrax
Raxibacumab (ABthrax), a human IgG1 monoclonal antibody, targets the protective antigen (PA) of Bacillus anthracis. It inhibits the toxic impact of anthrax by obstructing the PA's attachment to host cell receptors, preventing the subsequent harmful effects. This compound is utilized in anti-anthrax research [1] [2].
Raxibacumab
Raxibacumab
😃Good
Catalog No. T78310Alias ABthraxCas No. 565451-13-0
Raxibacumab (ABthrax), a human IgG1 monoclonal antibody, targets the protective antigen (PA) of Bacillus anthracis. It inhibits the toxic impact of anthrax by obstructing the PA's attachment to host cell receptors, preventing the subsequent harmful effects. This compound is utilized in anti-anthrax research [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | Inquiry | Backorder | |
| 5 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Raxibacumab (ABthrax), a human IgG1 monoclonal antibody, targets the protective antigen (PA) of Bacillus anthracis. It inhibits the toxic impact of anthrax by obstructing the PA's attachment to host cell receptors, preventing the subsequent harmful effects. This compound is utilized in anti-anthrax research [1] [2]. |
| In vivo | Raxibacumab, administered intravenously at doses of 150 μg/kg or 300 μg/kg in a single dose, significantly improved the prognosis in rats when given within 6 hours after initial exposure to lethal anthrax toxin (LeTx) [3]. |
| Alias | ABthrax |
| Cas No. | 565451-13-0 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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