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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $38 | 5 days | |
5 mg | $59 | 7-10 days | |
1 mL x 10 mM (in DMSO) | $63 | 7-10 days |
Description | Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively). |
In vivo | Ro 41-1049 (20 mg/kg) pretreatment significantly increases dopamine formation following L-dopa administration (100 mg/kg IP) while decreasing the formation of 3,4-dihydroxyphenylacetic acid and homovanillic acid. Ro 41-1049 (1-50 mg/kg; intraperitoneal injection; for 3 hours; Sprague-Dawley rats) treatment inhibits dopamine metabolite formation and increases dopamine levels in a dose-dependent fashion [2]. |
Molecular Weight | 301.77 |
Formula | C12H13ClFN3OS |
Cas No. | 127917-66-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 32 mg/mL (106.04 mM) H2O: 25 mg/mL (82.84 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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