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RY796
🥰Excellent
Catalog No. T16815Cas No. 1393441-53-6
Alias RY 796
RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders.
RY796
🥰Excellent
Purity: 98.59%
Catalog No. T16815Alias RY 796Cas No. 1393441-53-6
RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $90 | In Stock |
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Purity:98.59%
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Product Introduction
Bioactivity
Chemical Properties
| Description | RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders. |
| Targets&IC50 | Kv2.2:0.09 μM, Kv2.1:0.25 μM |
| In vitro | RY796 is a potent selective voltage-gated potassium (KV2) channel inhibitor with IC50 values of 0.25 μM and 0.09 μM for KV2.1 and KV2.2, respectively. [1] |
| In vivo | Inhibition of Kv2.x channel by RY796 enhanced GSIS in isolated wild-type (WT) mice and human islets. [2] |
| Alias | RY 796 |
| Molecular Weight | 353.46 |
| Formula | C21H27N3O2 |
| Cas No. | 1393441-53-6 |
| Smiles | C(N[C@H](C)C1=CC=CC=C1)(=O)C2=C(N(C)C)C=CC(NC(C(C)C)=O)=C2 |
| Relative Density. | 1.132 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (226.33 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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