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SEC inhibitor KL-1 (KL-1) is a potent, selective super elongation complex (SEC) inhibitor that exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM) and disrupts the interaction between the SEC scaffolding protein AFF4.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $57 | In Stock | |
5 mg | $139 | In Stock | |
10 mg | $222 | In Stock | |
25 mg | $379 | In Stock | |
50 mg | $572 | In Stock | |
100 mg | $813 | In Stock | |
1 mL x 10 mM (in DMSO) | $153 | In Stock |
Description | SEC inhibitor KL-1 (KL-1) is a potent, selective super elongation complex (SEC) inhibitor that exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM) and disrupts the interaction between the SEC scaffolding protein AFF4. |
Alias | KL-1 |
Molecular Weight | 345.78 |
Formula | C18H16ClNO4 |
Cas No. | 900308-84-1 |
Smiles | COc1cccc(c1)C(=O)\C=C(/O)C(=O)Nc1cc(Cl)ccc1C |
Relative Density. | 1.339 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 41.67 mg/mL (120.51 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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