Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

SLF

🥰Excellent
Catalog No. T13888Cas No. 195513-96-3

SLF is a synthetic ligand for FKBP12, which increases Ca2+ efflux and protein synthesis to improve skeletal muscle function, and is used in the study of central nervous system diseases and cancer.

SLF

SLF

🥰Excellent
Purity: 99.91%
Catalog No. T13888Cas No. 195513-96-3
SLF is a synthetic ligand for FKBP12, which increases Ca2+ efflux and protein synthesis to improve skeletal muscle function, and is used in the study of central nervous system diseases and cancer.
Pack SizePriceAvailabilityQuantity
2 mg73 €In Stock
Bulk & Custom
Add to Cart
Questions
View More
Select Batch
Purity:99.91%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
SLF is a synthetic ligand for FKBP12, which increases Ca2+ efflux and protein synthesis to improve skeletal muscle function, and is used in the study of central nervous system diseases and cancer.
Targets&IC50
FKBP12:2.6 μM, FKBP51:3.1 μM
In vitro
SLF is a synthetic ligand for FK506-binding protein (FKBP) with an IC50 of 2.6 μM for FKBP12 and an affinity of 3.1 μM for FKBP51. [1][2]
Chemical Properties
Molecular Weight524.65
FormulaC30H40N2O6
Cas No.195513-96-3
SmilesC(C(C(CC)(C)C)=O)(=O)N1[C@H](C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(N)=CC=C3)=O)CCCC1
Relative Density.1.161 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (152.48 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9060 mL9.5302 mL19.0603 mL95.3016 mL
5 mM0.3812 mL1.9060 mL3.8121 mL19.0603 mL
10 mM0.1906 mL0.9530 mL1.9060 mL9.5302 mL
20 mM0.0953 mL0.4765 mL0.9530 mL4.7651 mL
50 mM0.0381 mL0.1906 mL0.3812 mL1.9060 mL
100 mM0.0191 mL0.0953 mL0.1906 mL0.9530 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy SLF | purchase SLF | SLF cost | order SLF | SLF chemical structure | SLF in vitro | SLF formula | SLF molecular weight