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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $133 | In Stock | |
5 mg | $302 | In Stock | |
10 mg | $447 | In Stock | |
25 mg | $738 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,380 | In Stock | |
500 mg | $2,790 | In Stock | |
1 mL x 10 mM (in DMSO) | $289 | In Stock |
Description | AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266. |
Targets&IC50 | Androgen receptor: |
In vitro | AR antagonist 1 (compound 29) is the ligand for the target ligase of ARD-266, a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. AR antagonist 1 exhibits micromolar binding affinity to its E3 ligase complex and can be effectively used in designing potent and efficient PROTAC degraders. |
Molecular Weight | 278.78 |
Formula | C15H19ClN2O |
Cas No. | 1818885-54-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (215.22 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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