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Spiraeoside
🥰Excellent
Catalog No. TN2234Cas No. 20229-56-5
Alias Quercetin 4′-O-glucoside
Spiraeoside (Quercetin 4′-O-glucoside) is a compound that can be extracted from red onion skins. It exhibits antioxidant, anti-allergy, anti-inflammatory, and anti-tumor activities. It protects human myocardial cells from high glucose-induced damage, oxidative stress, and apoptosis by activating the PI3K/Akt/Nrf2 pathway. It also inhibits mast cell activation and IgE-mediated allergic reactions by suppressing phospholipase C-γ-mediated signaling.
Spiraeoside
🥰Excellent
Catalog No. TN2234Alias Quercetin 4′-O-glucosideCas No. 20229-56-5
Spiraeoside (Quercetin 4′-O-glucoside) is a compound that can be extracted from red onion skins. It exhibits antioxidant, anti-allergy, anti-inflammatory, and anti-tumor activities. It protects human myocardial cells from high glucose-induced damage, oxidative stress, and apoptosis by activating the PI3K/Akt/Nrf2 pathway. It also inhibits mast cell activation and IgE-mediated allergic reactions by suppressing phospholipase C-γ-mediated signaling.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $240 | In Stock | |
| 5 mg | $610 | In Stock | |
| 10 mg | $910 | In Stock | |
| 25 mg | $1,550 | In Stock | |
| 50 mg | $2,330 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Spiraeoside (Quercetin 4′-O-glucoside) is a compound that can be extracted from red onion skins. It exhibits antioxidant, anti-allergy, anti-inflammatory, and anti-tumor activities. It protects human myocardial cells from high glucose-induced damage, oxidative stress, and apoptosis by activating the PI3K/Akt/Nrf2 pathway. It also inhibits mast cell activation and IgE-mediated allergic reactions by suppressing phospholipase C-γ-mediated signaling. |
| In vitro | Spiraeoside attenuated the high glucose (HG) -induced decline in cell viability and increased levels of the myocardial enzymes lactate dehydrogenase and aspartate aminotransferase in AC16 cells. Spiraeoside protects AC16 cells from HG-induced oxidative stress, cell damage and apoptosis. The protective effect of Spiraeoside is regulated by the PI3K/Akt/Nrf2 signaling pathway. [1] Spiraeoside inhibits IGE-mediated mast cell activation and anaphylaxis by inhibiting PLC-γ2/MAPK signaling in Lyn induced mast cells. [2] |
| In vivo | Spiraeoside (200 mg/kg orally) improved sperm count, motility and testicular morphology in rats. [3] |
| Alias | Quercetin 4′-O-glucoside |
| Molecular Weight | 464.38 |
| Formula | C21H20O12 |
| Cas No. | 20229-56-5 |
| Smiles | O=C1C=2C(OC(=C1O)C3=CC(O)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3)=CC(O)=CC2O |
| Relative Density. | 1.809g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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