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Sucralose

Catalog No. T1399Cas No. 56038-13-2
Alias Trichlorosucrose, E955

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Sucralose

Sucralose

Purity: 99.93%
Catalog No. T1399Alias Trichlorosucrose, E955Cas No. 56038-13-2
Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.
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5 g$29In Stock
10 g$38In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.
In vitro
Using technetium-99m ((99m)Tc) to trace the morphology of erythrocytes in mice, along with the distribution of tissues traced by sodium pertechnetate (Na(99m)TcO(4)) and technetium-99m diethylenetriaminepentaacetate ((99m)Tc-DTPA), the impact of Sucralose on blood components was assessed. The results indicated that the blood components and cellular morphology of erythrocytes remained unchanged.
In vivo
The co-administration of peas and Sucralose to enteroendocrine cells induces higher levels of CCK (cholecystokinin) and GLP-1 (glucagon-like peptide-1) compared to their individual administration.
AliasTrichlorosucrose, E955
Chemical Properties
Molecular Weight397.63
FormulaC12H19Cl3O8
Cas No.56038-13-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 73 mg/mL (183.6 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 50 mg/mL (125.75 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.5149 mL12.5745 mL25.1490 mL125.7450 mL
5 mM0.5030 mL2.5149 mL5.0298 mL25.1490 mL
10 mM0.2515 mL1.2575 mL2.5149 mL12.5745 mL
20 mM0.1257 mL0.6287 mL1.2575 mL6.2873 mL
50 mM0.0503 mL0.2515 mL0.5030 mL2.5149 mL
100 mM0.0251 mL0.1257 mL0.2515 mL1.2575 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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