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Tamerit

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Purity:100%

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COA HNMR HPLC

Tamerit

Catalog No. T5837Cas No. 20666-12-0

Tamerit as an efficient inhibitor of oxidative burst in monocytes.

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500 mg	$41	In Stock

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Product Introduction

Bioactivity

Description

Tamerit as an efficient inhibitor of oxidative burst in monocytes.

In vitro

Oxidative burst responses of monocytes stimulated with PMA were strongly inhibited at Tamerit concentration ranging from 10-500 mg/ml, less efficient inhibitor was Tamerit in E. coli stimulated monocytes (inhibition range was from 50-500 mg/ml Tamerit). Tamerit inhibited PMC oxidative burst only in range 100-500 mg/ml Tamerit. Tamerit as an efficient inhibitor of oxidative burst in monocytes. ROS generation in monocytes/macrophages has been found to be important for LPS-driven production of several proinflammatory cytokines, Tamerit may exsert its antiinflammatory effects through monocyte/macrophage oxidative burst inhibition.

Chemical Properties

Molecular Weight	199.14
Formula	C8H6N3NaO2
Cas No.	20666-12-0

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 5.45 mg/mL (27.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0216 mL	25.1080 mL	50.2159 mL	251.0796 mL
5 mM	1.0043 mL	5.0216 mL	10.0432 mL	50.2159 mL
10 mM	0.5022 mL	2.5108 mL	5.0216 mL	25.1080 mL
20 mM	0.2511 mL	1.2554 mL	2.5108 mL	12.5540 mL

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In Vivo Formulation Calculator (Clear solution)

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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Keywords

LuminolInhibitorTameritinhibit