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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $149 | In Stock |
Description | TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ. |
In vitro | TBK1-IN-1 (1-100 μM; 72 h) inhibits the growth of A549 and LLC cells in a dose-dependent manner and suppresses the phosphorylation of downstream signaling effector protein S6K of TBK1[1]. |
Molecular Weight | 491.63 |
Formula | C27H37N7O2 |
Cas No. |
Storage | store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (163.40 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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