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Telekin

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Purity:99.97%

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COA HNMR HPLC

Telekin

Catalog No. T9144Cas No. 6752-90-5

Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells

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Pack Size	Price	Availability
1 mg	$133	In Stock
5 mg	$302	In Stock
10 mg	$453	In Stock
25 mg	$747	In Stock
50 mg	$1,050	In Stock
1 mL x 10 mM (in DMSO)	$276	In Stock

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Product Introduction

Bioactivity

Description	Telekin, a eudesmane-type sesquiterpene lactone compound isolated from Chinese folk medicine Carpesium divaricatum, has been reported to strongly inhibit the proliferation of cancer cells
In vitro	telekin activates the mitochondria-mediated apoptotic pathway in hepatocellular carcinoma cells and may merit further investigation as a potential therapeutic agent for the treatment of hepatocellular carcinoma[1].

Chemical Properties

Molecular Weight	248.32
Formula	C15H20O3
Cas No.	6752-90-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/ml (110.74 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0271 mL	20.1353 mL	40.2706 mL	201.3531 mL
5 mM	0.8054 mL	4.0271 mL	8.0541 mL	40.2706 mL
10 mM	0.4027 mL	2.0135 mL	4.0271 mL	20.1353 mL
20 mM	0.2014 mL	1.0068 mL	2.0135 mL	10.0677 mL
50 mM	0.0805 mL	0.4027 mL	0.8054 mL	4.0271 mL
100 mM	0.0403 mL	0.2014 mL	0.4027 mL	2.0135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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Tech Support

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Keywords

HepG-2Carpesium divaricatuminhibitApoptosisInhibitoranticancerTelekinsesquiterpene lactone