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TFC-007
🥰Excellent
Catalog No. T24870Cas No. 927878-49-7
Alias TFC007
TFC-007 is a selective and efficient hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, suppressing inflammatory factors. It can be used to synthesize H-PGDS degrader PROTAC (H-PGDS)-1 and study cedar pollen-induced guinea pig allergic rhinitis.
TFC-007
🥰Excellent
Catalog No. T24870Alias TFC007Cas No. 927878-49-7
TFC-007 is a selective and efficient hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, suppressing inflammatory factors. It can be used to synthesize H-PGDS degrader PROTAC (H-PGDS)-1 and study cedar pollen-induced guinea pig allergic rhinitis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $128 | In Stock | |
| 5 mg | $290 | In Stock | |
| 10 mg | $445 | In Stock | |
| 25 mg | $735 | In Stock | |
| 50 mg | $987 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | TFC-007 is a selective and efficient hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, suppressing inflammatory factors. It can be used to synthesize H-PGDS degrader PROTAC (H-PGDS)-1 and study cedar pollen-induced guinea pig allergic rhinitis. |
| Targets&IC50 | HPGDS:83 nM |
| In vitro | TFC-007 is a highly selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS), inhibiting H-PGDS enzyme with high activity and an IC50 value of 83 nM. [1] |
| Alias | TFC007 |
| Molecular Weight | 487.55 |
| Formula | C27H29N5O4 |
| Cas No. | 927878-49-7 |
| Smiles | O=C(NC1=CC=C(C=C1)N2CCC(C(=O)N3CCOCC3)CC2)C4=CN=C(N=C4)OC=5C=CC=CC5 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble) |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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