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TL8-506
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Catalog No. T60977Cas No. 1268163-15-0
Alias TL8506
TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammation and autoimmune diseases.
TL8-506
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Purity: 95%
Catalog No. T60977Alias TL8506Cas No. 1268163-15-0
TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammation and autoimmune diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,230 | 6-8 weeks | |
| 50 mg | $1,610 | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks |
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Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammation and autoimmune diseases. |
| Targets&IC50 | TLR8:30 nM (EC50) |
| In vitro | TL8-506 is a highly selective TLR8 agonist with a half-maximal effective concentration (EC50) of 30 nM. [1] |
| Alias | TL8506 |
| Molecular Weight | 331.37 |
| Formula | C20H17N3O2 |
| Cas No. | 1268163-15-0 |
| Smiles | N#CC1=CC=CC(=C1)C2=CC=C3C=C(C(=O)OCC)CC(=NC3=C2)N |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (30.18 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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