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VA-K-14 hydrochloride
🥰Excellent
Catalog No. T29087Cas No. 1171341-19-7
Alias VAK14 Hydrochloride, VA-K-14 HCl, VAK14 HCl, VA K 14 HCl
VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
VA-K-14 hydrochloride
🥰Excellent
Purity: 98.01%
Catalog No. T29087Alias VAK14 Hydrochloride, VA-K-14 HCl, VAK14 HCl, VA K 14 HClCas No. 1171341-19-7
VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $54 | In Stock | |
| 5 mg | $127 | In Stock | |
| 10 mg | $196 | In Stock | |
| 25 mg | $396 | In Stock | |
| 50 mg | $645 | In Stock | |
| 100 mg | $987 | In Stock |
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Purity:98.01%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling. |
| Targets&IC50 | TSHR:12.3 μM |
| Alias | VAK14 Hydrochloride, VA-K-14 HCl, VAK14 HCl, VA K 14 HCl |
| Molecular Weight | 341.86 |
| Formula | C18H16ClN3S |
| Cas No. | 1171341-19-7 |
| Smiles | Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (160.88 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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