Shopping Cart

Remove All

Your shopping cart is currently empty

Vasicinone

Select Batch

Purity:97.92%

Resource Download

COA HPLC HNMR

Vasicinone

Catalog No. TC0039Cas No. 486-64-6

Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$105	In Stock
5 mg	$322	In Stock
10 mg	$478	In Stock
25 mg	$772	In Stock
50 mg	$1,050	In Stock
1 mL x 10 mM (in DMSO)	$279	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Vasicinone"

Product Introduction

Bioactivity

Description

In vitro

The aerial parts of Peganum harmala L. (APP) is a well-known and effective herbal medicine in China, and has been commonly used for treating various ailments, including cough and asthma. OBJECTIVES: To evaluate the antitussive, expectorant, and bronchodilating effects of the quinazoline alkaloids (±)-vasicine (VAS), deoxyvasicine (DVAS) (both isolated from the alkaloid fraction of APP) and (±)-Vasicinone (VAO) (synthesized from VAS). CONCLUSIONS:Quinazoline alkaloids VAS, VAO, and DVAS have significant antitussive, expectorant, and bronchodilating activities. VAS, VAO, and DVAS are the active ingredients in APP, which can be used to treat respiratory disease.

Chemical Properties

Molecular Weight	202.21
Formula	C11H10N2O2
Cas No.	486-64-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12 mg/mL (59.34 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9454 mL	24.7268 mL	49.4535 mL	247.2677 mL
5 mM	0.9891 mL	4.9454 mL	9.8907 mL	49.4535 mL
10 mM	0.4945 mL	2.4727 mL	4.9454 mL	24.7268 mL
20 mM	0.2473 mL	1.2363 mL	2.4727 mL	12.3634 mL
50 mM	0.0989 mL	0.4945 mL	0.9891 mL	4.9454 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc