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Vasicinone

🥰Excellent
Catalog No. TC0039Cas No. 486-64-6

Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.

Vasicinone

Vasicinone

🥰Excellent
Purity: 97.92%
Catalog No. TC0039Cas No. 486-64-6
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.
Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$263In Stock
10 mg$396In Stock
25 mg$648In Stock
50 mg$912In Stock
100 mg$1,220In Stock
1 mL x 10 mM (in DMSO)$235In Stock
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Purity:97.92%
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Product Introduction

Bioactivity
Description
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803.
In vitro
The aerial parts of Peganum harmala L. (APP) is a well-known and effective herbal medicine in China, and has been commonly used for treating various ailments, including cough and asthma. OBJECTIVES: To evaluate the antitussive, expectorant, and bronchodilating effects of the quinazoline alkaloids (±)-vasicine (VAS), deoxyvasicine (DVAS) (both isolated from the alkaloid fraction of APP) and (±)-Vasicinone (VAO) (synthesized from VAS). CONCLUSIONS:Quinazoline alkaloids VAS, VAO, and DVAS have significant antitussive, expectorant, and bronchodilating activities. VAS, VAO, and DVAS are the active ingredients in APP, which can be used to treat respiratory disease.
Chemical Properties
Molecular Weight202.21
FormulaC11H10N2O2
Cas No.486-64-6
SmilesO[C@H]1CCn2c1nc1ccccc1c2=O
Relative Density.1.5g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 12 mg/mL (59.34 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.9454 mL24.7268 mL49.4535 mL247.2677 mL
5 mM0.9891 mL4.9454 mL9.8907 mL49.4535 mL
10 mM0.4945 mL2.4727 mL4.9454 mL24.7268 mL
20 mM0.2473 mL1.2363 mL2.4727 mL12.3634 mL
50 mM0.0989 mL0.4945 mL0.9891 mL4.9454 mL

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