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(S,R,S)-AHPC-C10-NH2 dihydrochloride
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Catalog No. T18661Cas No. 2341796-75-4
Alias VH032-linker 10, VH032-C10-NH2 dihydrochloride, VH032 amide-alkylC10-amine
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate, incorporating an (S,R,S)-AHPC-based VHL ligand and a linker[1].
(S,R,S)-AHPC-C10-NH2 dihydrochloride
😃Good
Catalog No. T18661Alias VH032-linker 10, VH032-C10-NH2 dihydrochloride, VH032 amide-alkylC10-amineCas No. 2341796-75-4
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate, incorporating an (S,R,S)-AHPC-based VHL ligand and a linker[1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $385 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | (S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate, incorporating an (S,R,S)-AHPC-based VHL ligand and a linker[1]. |
| In vitro | PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| Alias | VH032-linker 10, VH032-C10-NH2 dihydrochloride, VH032 amide-alkylC10-amine |
| Molecular Weight | 686.78 |
| Formula | C33H53Cl2N5O4S |
| Cas No. | 2341796-75-4 |
| Smiles | CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCCN)O.Cl.Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 200 mg/mL (291.21 mM) DMSO: 200 mg/mL (291.21 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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