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(S,R,S)-AHPC-PEG1-N3

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Catalog No. T17920Cas No. 2101200-09-1
Alias VHL Ligand-Linker Conjugates 9, VH032-PEG1-N3, E3 ligase Ligand-Linker Conjugates 3

(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC-based VHL ligand and a 1-unit PEG linker used in PROTAC technology.

(S,R,S)-AHPC-PEG1-N3

(S,R,S)-AHPC-PEG1-N3

🥰Excellent
Catalog No. T17920Alias VHL Ligand-Linker Conjugates 9, VH032-PEG1-N3, E3 ligase Ligand-Linker Conjugates 3Cas No. 2101200-09-1
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC-based VHL ligand and a 1-unit PEG linker used in PROTAC technology.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$77In Stock
10 mg$113In Stock
25 mg$189In Stock
50 mg$278In Stock
100 mg$455In Stock
200 mg$783In Stock
1 mL x 10 mM (in DMSO)$100In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC-based VHL ligand and a 1-unit PEG linker used in PROTAC technology.
AliasVHL Ligand-Linker Conjugates 9, VH032-PEG1-N3, E3 ligase Ligand-Linker Conjugates 3
Chemical Properties
Molecular Weight557.67
FormulaC26H35N7O5S
Cas No.2101200-09-1
SmilesC([C@@H](NC(COCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (179.32 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7932 mL8.9659 mL17.9318 mL89.6588 mL
5 mM0.3586 mL1.7932 mL3.5864 mL17.9318 mL
10 mM0.1793 mL0.8966 mL1.7932 mL8.9659 mL
20 mM0.0897 mL0.4483 mL0.8966 mL4.4829 mL
50 mM0.0359 mL0.1793 mL0.3586 mL1.7932 mL
100 mM0.0179 mL0.0897 mL0.1793 mL0.8966 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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