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α-Cyclodextrin

🥰Excellent
Catalog No. T17303Cas No. 10016-20-3
Alias NSC-269470, NSC269470, NSC 269470, Alfadex

α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.

α-Cyclodextrin
Other Forms of α-Cyclodextrin:
α-Cyclodextrin (hydrate)T3541451211-51-9
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α-Cyclodextrin

🥰Excellent
Purity: 98.27%
Catalog No. T17303Alias NSC-269470, NSC269470, NSC 269470, AlfadexCas No. 10016-20-3
α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
Pack SizePriceAvailabilityQuantity
1 g$42 In Stock
1 mL x 10 mM (in DMSO)$29 In Stock
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Purity:98.27%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
In vivo
α-Cyclodextrin preferentially reduces blood levels of saturated and trans fats in the LDL receptor knockout mice[2]. Two independent in vivo biological test systems were used, a single cell Xenopus oocyte with expressed human aquaporin for cell hydration studies and the nematode Caenorhabditis elegans for testing life span in the treated animals. α-Cyclodextrin was found to enhance water uptake through aquaporins of oocytes. Furthermore, α-Cyclodextrin promoted longevity in C. elegans[3].
AliasNSC-269470, NSC269470, NSC 269470, Alfadex
Chemical Properties
Molecular Weight972.84
FormulaC36H60O30
Cas No.10016-20-3
SmilesC(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]
Relative Density.1.483 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 40 mg/mL (41.12 mM), Sonication is recommended.
DMSO: 100 mg/mL (102.79 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.0279 mL5.1396 mL10.2792 mL51.3959 mL
5 mM0.2056 mL1.0279 mL2.0558 mL10.2792 mL
10 mM0.1028 mL0.5140 mL1.0279 mL5.1396 mL
20 mM0.0514 mL0.2570 mL0.5140 mL2.5698 mL
DMSO
1mg5mg10mg50mg
50 mM0.0206 mL0.1028 mL0.2056 mL1.0279 mL
100 mM0.0103 mL0.0514 mL0.1028 mL0.5140 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

α-CyclodextrinαCyclodextrinα CyclodextrinInhibitorinhibitalpha-Cyclodextrina-Cyclodextrin
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