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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $82 | 5 days |
Description | 10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain. |
In vivo | 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) selectively converts to 17β-estradiol exclusively within the brain. As an E2-bioprecursor, DHED represents a promising strategy for targeted delivery of E2 to the brain, potentially offering an effective treatment for hot flushes. |
Alias | DHED |
Molecular Weight | 288.38 |
Formula | C18H24O3 |
Cas No. | 549-02-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (866.91 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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