Shopping Cart
- Remove All
Your shopping cart is currently empty
10NH2-11F-Camptothecin TFA
😃Good
Catalog No. T87727Cas No. 2873461-64-2
10NH2-11F-Camptothecin TFA, a Camptothecin analogue, functions as an ADC cytotoxin for antibody-drug conjugates (ADCs) synthesis. It exhibits anticancer properties (WO2022246576A1; compound 140) [1].
10NH2-11F-Camptothecin TFA
😃Good
Catalog No. T87727Cas No. 2873461-64-2
10NH2-11F-Camptothecin TFA, a Camptothecin analogue, functions as an ADC cytotoxin for antibody-drug conjugates (ADCs) synthesis. It exhibits anticancer properties (WO2022246576A1; compound 140) [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "10NH2-11F-Camptothecin TFA"
Dexamethasone
Cited
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
ADC CytotoxinAntibacterialAntibioticAutophagyComplement SystemGlucocorticoid ReceptorIL ReceptorMitophagySARS-CoV
- $29
Size
QTY
CitedMethotrexate Cited
WR19039, NCI-C04671, CL14377, Amethopterin
T148559-05-2
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
- $38
Size
QTY
CitedPaclitaxel Cited
Taxol, NSC 125973
T096833069-62-4
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
- $34
Size
QTY
CitedCamptothecin Cited
NSC-100880, CPT, Campathecin, (S)-(+)-Camptothecin
T11237689-03-4
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis.
- $46
Size
QTY
CitedExatecan Mesylate
DX8951f
TQ0088169869-90-3
Exatecan Mesylate (DX8951f) is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).
- $30
Size
QTY
Doxorubicin hydrochloride Cited
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
- $34
Size
QTY
CitedFluticasone (propionate)
Fluticasone propionate, CCI-187881
T018880474-14-2
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
ADC CytotoxinEndogenous MetaboliteEstrogen/progestogen ReceptorGlucocorticoid ReceptorPhospholipaseVirus Protease
- $45
Size
QTY
Exatecan
DX-8951f
T11249171335-80-1
Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in cancer research.
- $30
Size
QTY
Mertansine Cited
Maytansinoid DM1, DM1
T1992139504-50-0
Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.
- $30
Size
QTY
CitedDaunorubicin hydrochloride Cited
Rubidomycin hydrochloride, RP-13057 Hydrochloride, Daunorubicin HCl, Daunomycin HCl
T151123541-50-6
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
- $31
Size
QTY
CitedBudesonide
Rhinocort, Pulmicort, Entocort
T009451333-22-3
Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects against multiple cells types and mediators referred to allergic and nonallergic-mediated inflammatory. What's more, the anti-inflammatory action of budesonide has been revealed to contribute to the effectiveness of asthma.
Inquiry
Methotrexate disodium
T80037413-34-5
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
- $34
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | 10NH2-11F-Camptothecin TFA, a Camptothecin analogue, functions as an ADC cytotoxin for antibody-drug conjugates (ADCs) synthesis. It exhibits anticancer properties (WO2022246576A1; compound 140) [1]. |
| Molecular Weight | 495.38 |
| Formula | C22H17F4N3O6 |
| Cas No. | 2873461-64-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy 10NH2-11F-Camptothecin TFA | purchase 10NH2-11F-Camptothecin TFA | 10NH2-11F-Camptothecin TFA cost | order 10NH2-11F-Camptothecin TFA | 10NH2-11F-Camptothecin TFA chemical structure | 10NH2-11F-Camptothecin TFA formula | 10NH2-11F-Camptothecin TFA molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.