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3-Butynoic acid

3-Butynoic acid
3-Butynoic acid is a potent inhibitor of acyl CoA dehydrogenase, a substrate for the Zn-dependent flavoproteinase D-lactate dehydrogenase, and can be used to study lactic acid metabolism.
Catalog No. T78225Cas No. 2345-51-9

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3-Butynoic acid

Catalog No. T78225Cas No. 2345-51-9

3-Butynoic acid is a potent inhibitor of acyl CoA dehydrogenase, a substrate for the Zn-dependent flavoproteinase D-lactate dehydrogenase, and can be used to study lactic acid metabolism.
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Pack SizePriceAvailabilityQuantity
500 mg$438-10 weeks
1 g$728-10 weeks
1 mL x 10 mM (in DMSO)$308-10 weeks
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Product Introduction

Bioactivity
Description
3-Butynoic acid is a potent inhibitor of acyl CoA dehydrogenase, a substrate for the Zn-dependent flavoproteinase D-lactate dehydrogenase, and can be used to study lactic acid metabolism.
Chemical Properties
Molecular Weight84.07
FormulaC4H4O2
Cas No.2345-51-9
Storage & Solubility Information
Storagestore at low temperature | Shipping with blue ice.
Solubility Information
H2O: 20 mg/mL (237.90 mM), Sonication is recommended.
DMSO: 20 mg/mL (237.90 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM11.8948 mL59.4742 mL118.9485 mL594.7425 mL
5 mM2.3790 mL11.8948 mL23.7897 mL118.9485 mL
10 mM1.1895 mL5.9474 mL11.8948 mL59.4742 mL
20 mM0.5947 mL2.9737 mL5.9474 mL29.7371 mL
50 mM0.2379 mL1.1895 mL2.3790 mL11.8948 mL
100 mM0.1189 mL0.5947 mL1.1895 mL5.9474 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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