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5-Methyltetrahydrofolic acid

Catalog No. T13516Cas No. 134-35-0
Alias 5-Methyl THF

5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid.

5-Methyltetrahydrofolic acid

5-Methyltetrahydrofolic acid

Purity: 98.19%
Catalog No. T13516Alias 5-Methyl THFCas No. 134-35-0
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid.
Pack SizePriceAvailabilityQuantity
50 mg$39In Stock
100 mg$57In Stock
500 mg$129In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:98.19%
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Product Introduction

Bioactivity
Description
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid.
Alias5-Methyl THF
Chemical Properties
Molecular Weight459.46
FormulaC20H25N7O6
Cas No.134-35-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (119.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1765 mL10.8823 mL21.7647 mL108.8234 mL
5 mM0.4353 mL2.1765 mL4.3529 mL21.7647 mL
10 mM0.2176 mL1.0882 mL2.1765 mL10.8823 mL
20 mM0.1088 mL0.5441 mL1.0882 mL5.4412 mL
50 mM0.0435 mL0.2176 mL0.4353 mL2.1765 mL
100 mM0.0218 mL0.1088 mL0.2176 mL1.0882 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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