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5-Bromouridine
🥰Excellent
Catalog No. T36894Cas No. 957-75-5
5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand.
5-Bromouridine
🥰Excellent
Purity: 99.89%
Catalog No. T36894Cas No. 957-75-5
5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mg | $30 | In Stock | |
| 500 mg | $41 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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Purity:99.89%
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Product Introduction
Bioactivity
Chemical Properties
| Description | 5-Bromouridine is a uracil derivative with a broad spectrum of antitumor activity that induces apoptosis in cancer cells by inhibiting DNA synthesis.5-Bromouridine is also used as a marker for DNA and RNA, where the molecule is labeled with a radioisotope or pigment after being introduced into a DNA or RNA strand. |
| Molecular Weight | 323.1 |
| Formula | C9H11BrN2O6 |
| Cas No. | 957-75-5 |
| Smiles | O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(Br)=C2 |
| Relative Density. | 1.9322 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 80 mg/mL (247.6 mM), Sonication is recommended. PBS (pH 7.2): 2 mg/mL (6.19 mM), Sonication is recommended. DMSO: 80 mg/mL (247.6 mM), Sonication is recommended. DMF: 8 mg/mL (24.76 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMF/H2O/DMSO
DMF/H2O/DMSO
H2O/DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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