Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 |
Description | AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1). |
Targets&IC50 | pGSK3β:92 nM, PKCβ2:3.98 μM, p70 S6K:399 nM, PKA:84 nM, Akt1:5 nM, RSK1:568 nM |
In vitro | AKT-IN-2 (Compound 8) also inhibits P70S6K, PKA, PKCβ2, RSK1, and pGSK3β (IC50s: 0.399, 0.084, 3.98, 0.568, and 0.092 μM). |
Molecular Weight | 505.58 |
Formula | C25H34F3N7O |
CAS No. | 1295514-91-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AKT-IN-2 1295514-91-8 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt AKTIN2 AKT IN 2 inhibitor inhibit