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(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

Abz-FR-K(Dnp)-P-OH acetate is an excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1.

K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant, achieving 100% protein modification at 10 μM after 24 hours in vitro.

(S)-Methyl 6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate is a useful organic compound for research related to life sciences. The catalog number is T64462 and the CAS number is 73548-77-3.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylnon-8-enoic acid is a useful organic compound for research related to life sciences. The catalog number is T66542 and the CAS number is 1311933-83-1.

5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM.

(2R S)-6-PNG (6-Prenylnaringenin) is a novel natural histone deacetylase inhibitor with anticancer and antitumor activity, and it blocks T-type calcium channels to reduce neuropathic and visceral pain in mice.

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba with notable antioxidant properties.

6-S-(2-Cyanoethyl)-2’-deoxy-5’-O-DMTr-6-thioguanosine 3’-CED phosphoramidite [catalog number TNU1665] is an essential organic compound for life sciences research.

(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channels, activating Ba2+ currents with an EC50 of 32 nM.

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6304 and the CAS number is 71781-79-8.

Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside, an acylated kaempferol glucoside, can be extracted from the leaves of O. dentata and serves as a repellent for the fouling organism, the blue mussel M. edulis [1].

LTX-401, targets the Golgi apparatus, and is an oncolytic amino acid derivative.

S-(p-Nitrobenzyl)glutathione acts as a competitive inhibitor of glutathionase. Rat kidney microsomes convert this compound into associated cysteine derivatives. It serves as a research tool in investigating the catabolism of glutathione by the glutathionase system [1] [2].

(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor. Its formation occurs through the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6 via a 5- or 6-hydroxy duloxetine intermediate, followed by a catechol duloxetine intermediate. This compound effectively inhibits the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) across lipid membranes, with inhibition constants (Kis) of 266, 920, and 2,814 nM, respectively, for human transporters.

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue. The isomerase activity responsible for the conversion of leukotriene B4 (LTB4) to 6-trans LTB4 in rat kidney homogenates has also been implicated in its formation. 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase. The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

(S)-Erypoegin K is a potent anticancer agent with strong anti-proliferative activity against HL-60 cells, inducing apoptosis.

2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-3',5'-di-(O-p-toluoyl))riboside is a 2'-deoxy nucleoside and halo-nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleoside; Halo-nucleoside

m-Cresol, alpha,alpha,alpha-trifluoro-6-nitro-, p-nitrobenzoate is a bioactive chemical.

6-O-p-Coumaroyl-1,2-di-O-galloyl-b-D-glucopyranose is a useful organic compound for research related to life sciences and the catalog number is T130064.

(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66550 and the CAS number is 314771-88-5.

Nucleoside Derivatives - 6-Modified purine nucleosides; Protected nucleosides w/NH2/OH open

3,5,7-Trihydroxy-p-menth-1-en-6-one, 5-Tigloyl, 3 is a useful organic compound for research related to life sciences and the catalog number is T130192.

The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to be an artifact by these authors because it lacked the potency of the 5(S),6(R) isomer with respect to contraction of isolated guinea pig lung parenchymal strips. It has not been possible to isolate natural LXA4 from humans or other mammals in amounts sufficient for determination of absolute stereochemistry. Most authors refer to LXA4 as the 5(S)

Mnk1/2 inhibitor

6-O-p-Methoxycinnamoylcatalpol is a natural product for research related to life sciences. The catalog number is TN3190 and the CAS number is 121710-02-9.

2-Methyl-6-(p-tolyl)heptane-2,3-diol is a natural product for research related to life sciences. The catalog number is TN2778 and the CAS number is 117421-22-4.

K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for the K-Ras recruiting moiety and a PROTAC linker. It can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker Conjugate 6 is particularly useful in synthesizing PROTAC K-Ras Degrader-1, which achieves ≥70% degradation efficacy in SW1573 cells[1].

(S)-S-Benzyl 6-amino-2-(((benzyloxy)carbonyl)amino)hexanethioate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65508 and the CAS number is 69861-89-8.

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-2-O-acetyl-5-(O-p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1038.

Super-chelating agent & MRI contrast agent

(S,E)-2-Methyl-6-(p-tolyl)hept-3-en-2-ol is a useful organic compound for research related to life sciences and the catalog number is T125520.

(2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol is a useful organic compound for research related to life sciences and the catalog number is T67174.

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin is a natural product for research related to life sciences. The catalog number is TN2871 and the CAS number is 349545-02-4.

GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase with an IC50 of 3.47 μM. This compound exhibits remarkable antimicrobial activity, excellent central nervous system penetration, and inhibits cytochrome P450, specifically the CYP3A4 isoform [1].

(S,E)-2-Amino-6-(but-2-enamido)hexanoic acid is a useful organic compound for research related to life sciences and the catalog number is T64505.

Compound 40, NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal), a macrocyclic analogue of Ape13, acts as a potent APJ agonist with a Ki of 5.7 nM. It demonstrates favorable Gα12-biased signaling and possesses an enhanced in vivo half-life [1].

5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.

1-O-Cinnamoyl-6-O-p-coumaroyl-b-D-glucopyranose is a useful organic compound for research related to life sciences and the catalog number is T130425.

(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65610 and the CAS number is 154127-42-1.

p-Vinylphenyl O-[beta-D-apiofuranosyl-(1-6)]-beta-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN4730 and the CAS number is 112047-91-3.

2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside; Fluoro-modified nucleoside.

6'-(p-Hydroxybenzoyl)mussaenosidic acid is a useful organic compound for research related to life sciences. The catalog number is T124023 and the CAS number is 87667-61-6.

Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6287 and the CAS number is 1448779-19-8.

1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose is a natural product for research related to life sciences. The catalog number is TN5847 and the CAS number is 138195-49-0.