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Acetylatractylodinol

Catalog No. TN3340Cas No. 61582-39-6
Alias Tractylodinol acetate

Acetylatractylodinol (Tractylodinol acetate) is a natural product isolated from Atractylodes lancea, possesses antioxidant activity.

Acetylatractylodinol

Acetylatractylodinol

Purity: 99.52%
Catalog No. TN3340Alias Tractylodinol acetateCas No. 61582-39-6
Acetylatractylodinol (Tractylodinol acetate) is a natural product isolated from Atractylodes lancea, possesses antioxidant activity.
Pack SizePriceAvailabilityQuantity
1 mg$98In Stock
2 mg$148In Stock
5 mg$263In Stock
10 mg$392In Stock
25 mg$645In Stock
50 mg$886In Stock
1 mL x 10 mM (in DMSO)$238In Stock
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Purity:99.52%
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Product Introduction

Bioactivity
Description
Acetylatractylodinol (Tractylodinol acetate) is a natural product isolated from Atractylodes lancea, possesses antioxidant activity.
In vitro
METHODS AND RESULTS: From the rhizomes of Atractylodes lancea, 2-[(2'E)-3',7'-dimethyl-2',6'-octadienyl]-4-methoxy-6-methylphenol (1) was isolated as a new natural product. The compound showed strong inhibitory effects on 5-lipoxygenase (5-LOX) and cyclooxygenase-1 (COX-1), but exhibited only weak antioxidative activities [IC50 = 0.1 microM (5-LOX), 2 microM (COX-1), 9 microM (PMN/FMLP), 28 microM (PMNIOZ)]. Moreover, five new acetylenes were isolated and elucidated as (3Z,5E,11E)-tridecatriene-7,9-diynyl-1-O-(E)-ferulate (2), erythro-(1,3Z,11E)-tridecatriene-7,9-diyne-5,6-diyl diacetate (3), (1Z)-atractylodin (4), (1Z)-atractylodinol (5), (1Z)-Acetylatractylodinol (6) plus the known (4E,6E,12E)-tetradecatriene-8,10-diyne-1,3-diyl diacetate (7). CONCLUSIONS: Among the acetylenes, only 2 showed strong inhibition of 5-LOX and COX-1 activity (IC50 (5-LOX) = 3 microM, IC50 (COX-1) = 1 microM). In addition, the fatty acids linoleic acid, oleic acid and palmitic acid with previously established 5-LOX-/COX-1 inhibitory actions were identified as major constituents of the n-hexane extract and thus seem to contribute to the plant's in vitro activity.
AliasTractylodinol acetate
Chemical Properties
Molecular Weight240.25
FormulaC15H12O3
Cas No.61582-39-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (249.74 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1623 mL20.8117 mL41.6233 mL208.1165 mL
5 mM0.8325 mL4.1623 mL8.3247 mL41.6233 mL
10 mM0.4162 mL2.0812 mL4.1623 mL20.8117 mL
20 mM0.2081 mL1.0406 mL2.0812 mL10.4058 mL
50 mM0.0832 mL0.4162 mL0.8325 mL4.1623 mL
100 mM0.0416 mL0.2081 mL0.4162 mL2.0812 mL

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