Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 4-5 weeks | $ 110.00 | |
5 mg | 4-5 weeks | $ 458.00 | |
10 mg | 4-5 weeks | $ 853.00 |
Description | Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1]. |
Molecular Weight | 414.5 |
Formula | C17H22N2O6S2 |
CAS No. | 287405-51-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Apratastat 287405-51-0 Apoptosis Proteases/Proteasome MMP TNF inhibitor inhibit