Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 329.00 | |
5 mg | In stock | $ 798.00 | |
10 mg | In stock | $ 1,090.00 | |
25 mg | In stock | $ 1,650.00 | |
50 mg | 8-10weeks | $ 2,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 953.00 |
Description | BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM. |
Targets&IC50 | AAK1:0.9 nM, GAK:99 nM |
In vitro | BMT-124110 presents a cellular IC50 of 3.2 nM for AAK1[1]. |
In vivo | BMT-124110 is added directly to the spine by microion electrophoresis. Wind-induced activity decreased in 10 of the 14 animals.[1] |
Molecular Weight | 369.46 |
Formula | C21H27N3O3 |
CAS No. | 1679371-59-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (74.43 mM)
You can also refer to dose conversion for different animals. More
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BMT-124110 1679371-59-5 Neuroscience AAK1 (AP2 associated kinase 1) BMT124110 BMT 124110 inhibitor inhibit