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RSS0680

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Catalog No. T74643Cas No. 2769753-48-0

RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be used to study diseases caused by kinase abnormalities.

RSS0680

RSS0680

🥰Excellent
Purity: 98.02%
Catalog No. T74643Cas No. 2769753-48-0
RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be used to study diseases caused by kinase abnormalities.
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1 mg$399In Stock
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Purity:98.02%
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Product Introduction

Bioactivity
Description
RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be used to study diseases caused by kinase abnormalities.
Chemical Properties
Molecular Weight1021.32
FormulaC52H64N10O6S3
Cas No.2769753-48-0
SmilesN(C=1N=C2C(=CSC2=CN1)C3=CC(NS(C)(=O)=O)=CC=C3)C4=CC=C(C=C4)N5CCN(CCCCCC(N[C@H](C(=O)N6[C@H](C(N[C@@H](C)C7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)[C@@](C)(C)C)=O)CC5
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (78.33 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.9791 mL4.8956 mL9.7913 mL48.9563 mL
5 mM0.1958 mL0.9791 mL1.9583 mL9.7913 mL
10 mM0.0979 mL0.4896 mL0.9791 mL4.8956 mL
20 mM0.0490 mL0.2448 mL0.4896 mL2.4478 mL
50 mM0.0196 mL0.0979 mL0.1958 mL0.9791 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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