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CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $39 | In Stock | |
5 mg | $98 | In Stock | |
10 mg | $147 | In Stock | |
25 mg | $249 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $548 | In Stock | |
500 mg | $1,170 | In Stock | |
1 mL x 10 mM (in DMSO) | $108 | In Stock |
Description | CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection. |
Targets&IC50 | MTH2 (cells):9.2 μM , hTh2 cells:31.6 μM , MTH1 (cells):3.7 μM , Th1 (human):26.9 μM, hTh1 cells:26.9 μM , MTH2:9.2 μM, MTH1:3.7 μM, hTh2 (human):31.6 μM |
In vitro | In 60A cells, CMP-5 (40 μM; 24 hours) inhibited the protein levels of p-BTK and pY(416)SRC[1]. |
Molecular Weight | 315.41 |
Formula | C21H21N3 |
Cas No. | 880813-42-3 |
Smiles | CCn1c2ccccc2c2cc(CNCc3ccccn3)ccc12 |
Relative Density. | 1.14 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (317.05 mM), Sonification is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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