Shopping Cart
- Remove All
Your shopping cart is currently empty
CO23
🥰Excellent
Catalog No. T10855Cas No. 1370363-74-8
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
CO23
🥰Excellent
Purity: 96.52%
Catalog No. T10855Cas No. 1370363-74-8
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $233 | In Stock | |
| 5 mg | $579 | In Stock | |
| 10 mg | $868 | In Stock | |
| 25 mg | $1,430 | In Stock | |
| 50 mg | $1,930 | In Stock | |
| 100 mg | $2,590 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "CO23"
Resmetirom
VIA-3196, MGL3196
T3595920509-32-6
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
- $33
Size
QTY
L-Thyroxine sodium
L-T4 sodium, LT4 sodium, Levothyroxine sodium
T2235555-03-8
L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.
- $47
Size
QTY
Carbimazole
Neomercazole, Carbimazol, Athyromazole
T095222232-54-8
Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease.
- $35
Size
QTY
PCO371
2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
T164421613373-33-3
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.
- $97
Size
QTY
Liothyronine sodium
Triostat, T3 Sodium salt, Sodium L-3,3',5-triiodothyronine, Cytomel, 3,3',5-Triiodo-L-thyronine sodium
T166955-06-1
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).
- $47
Size
QTY
2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE
BisOPP-A
T867224038-68-4
2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE is targets the thyroid stimulating hormone receptor (human)
- $50
Size
QTY
Liothyronine
Cited
Triiodothyronine, Tresitope, Lyothyronine, L-3,3',5-Triiodothyronine, 3,3',5-Triiodo-L-thyronine
T16536893-02-3
Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
- $36
Size
QTY
Cited2-Thiouracil
Thiouracil, Deracil
T1310141-90-2
2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.
- $29
Size
QTY
L-Thyroxine
T4, NSC 36397, Levothyroxine
T086451-48-9
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
- $31
Size
QTY
Tiratricol
3,3',5-Triiodothyroacetic acid
T160451-24-1
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
- $33
Size
QTY
Propylthiouracil
Pseudocapsaicin, NSC 70461, NSC 6498, 6-Propyl-2-thiouracil, 6-n-Propylthiouracil
T130951-52-5
Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.
- $33
Size
QTY
Methimazole
Thiamazole, Tapazole
T084060-56-0
Methimazole (Thiamazole) is an antithyroid compound with significant hepatotoxicity and is often used in the study of hyperthyroidism.
- $45
Size
QTY
Select Batch
Purity:96.52%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development. |
| In vivo | Intraperitoneal injection of CO23 (0.8-5.0 nmol/g) reduces about 50% of cholesterol. CO23(0.8, 2.5, and 5 nmol/g) increases Dio1 mRNA 5-, 10-, and 15-fold, respectively[1]. |
| Molecular Weight | 592.17 |
| Formula | C19H18I2N2O4 |
| Cas No. | 1370363-74-8 |
| Smiles | CC(C)c1cc(Oc2c(I)cc(CC3NC(=O)NC3=O)cc2I)ccc1O |
| Relative Density. | 1.878 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 225.0 mg/mL (380.0 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy CO23 | purchase CO23 | CO23 cost | order CO23 | CO23 chemical structure | CO23 in vivo | CO23 formula | CO23 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.